Search results for "Àcids grassos"

showing 8 items of 8 documents

Fatty Acids Composition of Blood Cell Membranes and Peripheral Inflammation in the PREDIMED Study: A Cross-Sectional Analysis

2019

There is limited evidence from epidemiological studies for the inflammatory or anti-inflammatory properties of fatty acids in blood cell membranes. Therefore, this study examined associations between baseline (n = 282) and 1-year (n = 143) changes in the levels of fatty acids in blood cell membranes with circulating inflammatory markers in older adults at high cardiovascular risk. The data for this cross-sectional analysis was obtained from a case-control study within the PREDIMED study. Linear regression with elastic net penalty was applied to test associations between measured fatty acids and inflammatory markers. Several fatty acids were associated with interferon-&gamma

Male0301 basic medicinemedicine.medical_specialtyCross-sectional studyÀcids grassoslcsh:TX341-641Inflammation030204 cardiovascular system & hematologyfatty acidsArticleBlood cell03 medical and health sciences0302 clinical medicine:Ciencias de la Salud::Medicina preventiva [Materias Investigacion]Internal medicinemedicineHumansFatty acidsAgedcell membranesAged 80 and overInflammationBlood Cells030109 nutrition & dieteticsNutrition and DieteticsChemistryCell MembraneInterleukinMiddle AgedPredimedPeripheralCell membranesCross-Sectional StudiesMembraneEndocrinologymedicine.anatomical_structureinflammationCase-Control StudiesCytokinesFemaleFatty acid compositionmedicine.symptomlcsh:Nutrition. Foods and food supplyMembranes cel·lularsFood ScienceNutrients
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Total and Subtypes of Dietary Fat Intake and its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiova…

2019

Background: The effect of dietary fat intake on the metabolic syndrome (MetS) and in turn on cardiovascular disease (CVD) remains unclear in individuals at high CVD risk. Objective: To assess the association between fat intake and MetS components in an adult Mediterranean population at high CVD risk. Design: Baseline assessment of nutritional adequacy in participants (n = 6560, men and women, 55&ndash

Blood GlucoseMaleMediterranean diethumanosPhysiologyÀcids grassos030204 cardiovascular system & hematologyOverweightDiet Mediterraneanchemistry.chemical_compound0302 clinical medicineRisk Factorsevaluación de riesgosMedicine030212 general & internal medicinemediana edadlípidos2. Zero hungerchemistry.chemical_classificationMetabolic Syndromeeducation.field_of_studyancianoNutrition and Dieteticsdietaresultado del tratamientofood and beveragesMiddle AgedLipidscardiovascular disease risk3. Good healthfat intakeTreatment OutcomeCardiovascular Diseasesdietary fatObesitatFemalemedicine.symptomlcsh:Nutrition. Foods and food supplyPolyunsaturated fatty acidglucosa sanguíneaMediterranean diet cardiovascular disease risk dietary fat fat intake fatty acidsLinoleic acidPopulationdislipidemiasenfermedades cardiovasculareslcsh:TX341-641Risk Assessmentfatty acidsArticle03 medical and health sciencesgrasas dietéticasMediterranean cooking:Ciencias de la Salud::Medicina preventiva [Materias Investigacion]Mediterranean dietCuina mediterràniafactores de riesgoHumansObesitycardiovascular diseaseseducationhiperglucemiaAgedDyslipidemiasbusiness.industryMalalties cardiovascularsHypertriglyceridemiamedicine.diseaseObesityDietary FatsDietCross-Sectional StudieschemistrySpainHyperglycemiaMetabolic syndromebusinessBiomarkersFood Scienceestudios transversalesNutrients
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Seafood Consumption, Omega-3 Fatty Acids Intake, and Life-Time Prevalence of Depression in the PREDIMED-Plus Trial.

2018

Background: The aim of this analysis was to ascertain the type of relationship between fish and seafood consumption, omega-3 polyunsaturated fatty acids (&omega

0301 basic medicineMaleeicosapentaenoic acidmodelos logísticoshumanosdepresiónencuestas sobre dietas0302 clinical medicineClinical trialsSurveys and QuestionnairesOdds RatioPrevalence030212 general & internal medicineDepressió psíquicamediana edadDietoteràpia2. Zero hungerancianoNutrition and Dieteticsintegumentary systemdietaDepressionEuropean researchFatty AcidsprevalenciaFishesfood and beveragesMiddle Ageddocosahexaenoic acidcociente de probabilidades relativasMental depressiondepressionChristian ministryFemaleomega-3lcsh:Nutrition. Foods and food supplyEuropean Regional Development Fundlcsh:TX341-641Àcids grassos omega-3Diet SurveysArticle03 medical and health sciencesalimentos del marDepression (economics)pecestrastorno depresivoEnvironmental healthPolitical scienceFatty Acids Omega-3ingesta energéticaOmega-3 fatty acidsAnimalsHumansácidos grasosAgedConsumption (economics)fishconducta alimentariaDepressive Disorder030109 nutrition & dieteticsDiet therapyLife timeFeeding BehaviorPredimedDietCross-Sectional StudiesLogistic ModelsSeafoodanimalesEnergy IntakeFood Scienceestudios transversalesAssaigs clínicsNutrients
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Signature of Circulating Biomarkers in Recurrent Non-Infectious Anterior Uveitis. Immunomodulatory Effects of DHA-Triglyceride. A Pilot Study

2021

The purpose of this study was to identify circulating biomarkers of recurrent non-infectious anterior uveitis (NIAU), and to address the anti-inflammatory effects of triglyceride containing docosahexaenoic acid (DHA-TG). A prospective multicenter study was conducted in 72 participants distributed into: patients diagnosed with recurrent NIAU in the quiescence stage (uveitis group (UG)

0301 basic medicineMedicine (General)medicine.medical_specialtyClinical BiochemistryÀcids grassos omega-3GastroenterologyArticlerecurrent anterior non-infectious uveitisUveitis03 medical and health scienceschemistry.chemical_compoundR5-9200302 clinical medicineOral administrationInternal medicineOmega-3 fatty acidsMedicineTriglicèridsStage (cooking)Triglyceridesomega-3 fatty acidsTriglyceridebusiness.industryInterleukintriglyceride of docosahexaenoic acidmedicine.diseasecytokinesCirculating biomarkers030104 developmental biologychemistryDocosahexaenoic acidUveïtis030221 ophthalmology & optometryTumor necrosis factor alphabusinessUveitisDiagnostics
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Intravitreal Docosahexaenoic Acid in a Rabbit Model: Preclinical Safety Assessment

2014

PurposeThe purpose of the present study was to evaluate the retinal toxicity of a single dose of intravitreal docosahexaenoic acid (DHA) in rabbit eyes over a short-term period.MethodsSixteen New Zealand albino rabbits were selected for this pre-clinical study. Six concentrations of DHA (Brudy Laboratories, Barcelona, Spain) were prepared: 10 mg/50 µl, 5 mg/50 µl, 2'5 mg/50 µl, 50 µg/50 µl, 25 µg/50 µl, and 5 µg/50 µl. Each concentration was injected intravitreally in the right eye of two rabbits. As a control, the vehicle solution was injected in one eye of four animals. Retinal safety was studied by slit-lamp examination, and electroretinography. All the rabbits were euthanized one week a…

MaleRetinal degenerationgenetic structuresÀcids grassosPharmacologyBiochemistryMicechemistry.chemical_compoundCorneaMedicine and Health SciencesRatolinsExperimentació animalDegeneració (Patologia)Multidisciplinarymedicine.diagnostic_testQFatty AcidsChromatographic TechniquesRDegeneration (Pathology)Animal ModelsLipidsChemistrymedicine.anatomical_structureNeurologyDocosahexaenoic acidPhysical SciencesMedicineRetinal DisordersRabbitsSafetyAnatomyResearch Articlemedicine.medical_specialtyHistologyDrug Research and DevelopmentDocosahexaenoic AcidsNew Zealand AlbinoScienceOcular AnatomyResearch and Analysis MethodsRetinaInjectionsAqueous HumorModel OrganismsOcular SystemElectroretinographyToxicity Tests AcutemedicineAnimalsFatty acidsGas ChromatographyPharmacologyDose-Response Relationship Drugbusiness.industrySignificant differenceBiology and Life SciencesRetinalmedicine.diseaseSurgeryVitreous BodyOphthalmologychemistryNeuro-OphthalmologyAnimal experimentationRabbit modelClinical MedicinebusinessElectroretinographyPLoS ONE
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Prenatal Omega-6:Omega-3 Ratio and Attention Deficit and Hyperactivity Disorder Symptoms

2019

Supported by the Spanish Institute of Health Carlos III (Co-funded by European Regional Development Fund “A way to make Europe”) (CP14/00108, PI16/00261, MS14/00108 [to J.J.]), the Agència de Gestió d’Ajuts Universitaris i de Recerca, Generalitat de Catalunya - Fons Social Europeu (2017 FI_B 00636 [to N.V-T.]), the Spanish Ministry of Science and Innovation (RYC-2012-10995 [to P.D.] and RYC-2011-08796 [to D.R.]), Obra Social Cajastur/Fundación Liberbank, Universidad de Oviedo, CIBERESP, Department of Health of the Basque Government, the Provincial Government of Gipuzkoa, the municipalities of the study area (Zumarraga, Urretxu, Legazpi, Azkoitia y Azpeitia y Beasain), Generalitat Valenciana…

MaleNeurobiologia del desenvolupamentTrastorns per dèficit d'atenció amb hiperactivitat en els infantsPediatricsmedicine.medical_specialtychildren long-chain polyunsaturated fatty acids neurodevelopment population-based cohortOffspringPopulationÀcids grassosRate ratioLogistic regressionAttention deficit disorder with hyperactivity in childrenlong-chain polyunsaturated fatty acids03 medical and health sciences0302 clinical medicinePregnancyFatty Acids Omega-6030225 pediatricsFatty Acids Omega-3medicineHumansProspective Studiespopulation-based cohortDevelopmental neurobiology030212 general & internal medicineFatty acidsChildeducationPrenatal Nutritional Physiological PhenomenaChildrenSubclinical infectionchemistry.chemical_classificationPregnancyeducation.field_of_studyneurodevelopmentbusiness.industryFetal Bloodmedicine.diseasechemistryAttention Deficit Disorder with HyperactivityDocosahexaenoic acidChild PreschoolPediatrics Perinatology and Child HealthFemalebusinessInfantsPolyunsaturated fatty acidThe Journal of Pediatrics
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Dietary α-Linolenic Acid, Marine ω-3 Fatty Acids, and Mortality in a Population With High Fish Consumption: Findings From the PREvención con DIeta ME…

2016

12 Páginas.-- 6 Tablas.-- 1 Figura

MaleGerontologyTime FactorsEpidemiologymodelos de riesgos proporcionaleshumanos030204 cardiovascular system & hematologychemistry.chemical_compound0302 clinical medicineRisk Factorsestudios prospectivosevaluación de riesgosMedicineNutsSudden cardian death030212 general & internal medicineFood scienceLongitudinal StudiesProspective Studiesmediana edadOriginal ResearchDiet and NutritionAged 80 and overchemistry.chemical_classificationeducation.field_of_studyancianoalpha-Linolenic aciddietaFactors de risc en les malaltiesHàbits alimentarisFatty Acidsω-3 fatty acidsFatty acids in human nutritionalpha-Linolenic Aciddistribución de la ji al cuadradoMiddle AgedCardiovascular systemnutritionCardiovascular DiseasesFemaleDietaCardiology and Cardiovascular MedicineNutritive Valueconducta de reducción del riesgoRisk factors in diseasesFood habitsPopulationenfermedades cardiovasculares030209 endocrinology & metabolismJuglansRisk Assessmentsudden cardiac death03 medical and health sciencesalimentos del marfactores de tiempoMediterranean cookingÀcids grassos en la nutricióFatty Acids Omega-3Cuina mediterràniaPeix com a alimentHumansfactores de riesgoanálisis multifactorialeducationOlive OilDieta -- Mediterrània Regió de laDieta mediterraneaácidos grasosα-linolenic acidAgedProportional Hazards ModelsSistema cardiovascularChi-Square Distributionbusiness.industryCorrectionFatty acidHàbits alimentaris -- Mediterrània Regió de laProtective FactorsFish consumptionPredimedDietnueceschemistrySeafoodSpainMultivariate Analysisvalor nutritivoestudios longitudinalesfatty acidbusinessRisk Reduction Behaviorácido alfa-linolénico
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Genome-Wide Association Study for Serum Omega-3 and Omega-6 Polyunsaturated Fatty Acids: Exploratory Analysis of the Sex-Specific Effects and Dietary…

2020

Many early studies presented beneficial effects of polyunsaturated fatty acids (PUFA) on cardiovascular risk factors and disease. However, results from recent meta-analyses indicate that this effect would be very low or nil. One of the factors that may contribute to the inconsistency of the results is that, in most studies, genetic factors have not been taken into consideration. It is known that fatty acid desaturase (FADS) gene cluster in chromosome 11 is a very important determinant of plasma PUFA, and that the prevalence of the single nucleotide polymorphisms (SNPs) varies greatly between populations and may constitute a bias in meta-analyses. Previous genome-wide association studies (GW…

0301 basic medicineFatty Acid DesaturasesMaleSíndrome metabòlicaDiet MediterraneanMediterranean populationchemistry.chemical_compoundDelta-5 Fatty Acid DesaturaseÀcids grassos saturatsRisk Factorsgeneticschemistry.chemical_classificationMetabolic Syndromeeducation.field_of_studyClinical Trials as TopicNutrition and DieteticsbiologyMiddle AgedPhenotypeTreatment OutcomeFemaleomega-3mediterranean populationlcsh:Nutrition. Foods and food supplypolyunsaturated fatty acidsPolyunsaturated fatty acidmedicine.medical_specialtyomega-6FADS1Fatty Acid ElongasesLinoleic acidPopulationlcsh:TX341-641Single-nucleotide polymorphismGenetic polymorphismsPolymorphism Single NucleotideArticlemetabolic syndrome03 medical and health sciencesSex FactorsInternal medicineFatty Acids Omega-6Fatty Acids Omega-3medicinesexHumansGenetic Predisposition to DiseaseSaturated fatty acidseducationAgedgenome-wide association study030109 nutrition & dieteticsPolimorfisme genèticFatty acidmedicine.disease030104 developmental biologyFatty acid desaturaseEndocrinologyCross-Sectional StudieschemistrySpainbiology.proteinGene-Environment InteractionheterogeneityMetabolic syndromepolymorphismsFood ScienceGenome-Wide Association Study
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